Start Submission Become a Reviewer

Reading: Leigh syndrome responsive to vitamin therapy

Download

A- A+
Alt. Display

Case Reports

Leigh syndrome responsive to vitamin therapy

Authors:

K. C. S. Dalpatadu ,

Lady Ridgeway Hospital for Children, Colombo 8, LK
X close

P. D. Ratnayake,

Lady Ridgeway Hospital for Children, Colombo 8
X close

P. M. G. Punchihewa

Lady Ridgeway Hospital for Children, Colombo 8, LK
X close

Abstract

We report a case of Leigh syndrome in a girl aged four years and eight months who presented to us with progressive ptosis and worsening ataxia with frequent falls on a background of development delay. The clinical profile, biochemical analysis and MRI findings were consistent with a diagnosis of Leigh syndrome. Her clinical course was that of infantile onset, mild, slowly progressive form. She was given multivitamin supplement aiming to provide high dose thiamine and showed a remarkable response with disappearance of ptosis and marked improvement in function in the speech domain and motor skills.

How to Cite: Dalpatadu KCS, Ratnayake PD, Punchihewa PMG. Leigh syndrome responsive to vitamin therapy. Sri Lanka Journal of Neurology. 2012;1(1):45–7. DOI: http://doi.org/10.4038/sljon.v1i1.119
Published on 30 Dec 2012.
Peer Reviewed

Downloads

  • PDF (EN)

    comments powered by Disqus