Case Reports
Leigh syndrome responsive to vitamin therapy
Authors:
K. C. S. Dalpatadu ,
Lady Ridgeway Hospital for Children, Colombo 8, LK
P. D. Ratnayake,
Lady Ridgeway Hospital for Children, Colombo 8
P. M. G. Punchihewa
Lady Ridgeway Hospital for Children, Colombo 8, LK
Abstract
We report a case of Leigh syndrome in a girl aged four years and eight months who presented to us with progressive ptosis and worsening ataxia with frequent falls on a background of development delay. The clinical profile, biochemical analysis and MRI findings were consistent with a diagnosis of Leigh syndrome. Her clinical course was that of infantile onset, mild, slowly progressive form. She was given multivitamin supplement aiming to provide high dose thiamine and showed a remarkable response with disappearance of ptosis and marked improvement in function in the speech domain and motor skills.
How to Cite:
Dalpatadu KCS, Ratnayake PD, Punchihewa PMG. Leigh syndrome responsive to vitamin therapy. Sri Lanka Journal of Neurology. 2012;1(1):45–7. DOI: http://doi.org/10.4038/sljon.v1i1.119
Published on
30 Dec 2012.
Peer Reviewed
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